CBASS

A minimal CRISPR polymerase produces decoy cyclic nucleotides to detect phage anti-defense proteins
Mar 28, 2025
Sullivan AE, Nabhani A, Schinkel K, Dinh DM, Duncan ML, Ednacot EMQ, Hoffman CRK, Izrailevsky DS, Kibby EM, Nagy TA, Nguyen CM, Tak U, Burroughs AM, Aravind L, ➤Whiteley AT†, Morehouse BR† (†co-cor. author) | BioRxiv 2025
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Bacterial cGAS-like enzymes produce 2′,3′-cGAMP to activate an ion channel that restricts phage replication
Jul 26, 2023
Tak U, Walth P, ➤Whiteley AT | BioRxiv 2023
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Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage defense
Jun 1, 2021
Govande AA, Duncan-Lowey B, Eaglesham JB, ➤Whiteley AT, Kranzusch PJ. | Cell Reports 2021
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