Solvent Guides
The following references should be available to affiliates of the Unversity of Colorado Boulder when accessed on the UCB wireless network. For individuals at other institutions, many of these should be available through your own organization's subscription to online journals.听
American Chemical Society Solvent Selection Tool
Developed by the ACS GCI Pharmaceutical Roundtable, this听allows you to select solvents based on their physical properties
MIT "Green" Alternatives Wizard
Search for a chemical to replace, a process to replace, an alternative chemical, or an alternative process using the听.
General Green Solvent Information
Capello, Christian, Ulrich Fischer, and Konrad Hungerbuhler. 鈥淲hat is a green solvent? A comprehensive framework for the environmental assessment of solvents.鈥澨Green Chemistry听9 (2007): 927-934. Web. DOI:听10.1039/B617536H
Jessop, Philip G. 鈥淪earching for green solvents.鈥澨Green Chemistry听13 (2011): 1391-1398. Web. DOI: 10.1039/c0gc00797h
Solvent Guides
Alfonsi, Kim. et. al. 鈥淕reen chemistry tools to influence a medicinal chemistry and research chemistry based organization.鈥澨Green Chemistry听10 (2008): 31-36. Web. DOI: 10.1039/b711717e
American Chemical Society Green Chemistry Institute Pharmaceutical Roundtable Solvent Selection Guide Version 2.0 issued March 21, 2011.听
Henderson, Richard K. et. al. 鈥淓xpanding GSK鈥檚 solvent selection guide 鈥 embedding sustainability into solvent selection starting at medicinal chemistry.鈥澨Green Chemistry听13 (2011): 854-862. Web. DOI: 10.1039/c0gc00918k
MacMillan, Donna S. et. al. 鈥淓valuation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide.鈥澨Green Chemistry听15 (2013): 596-600. Web. DOI: 10.1039/c2gc36900a
McGonagle, Fiona I. et. al. 鈥淒evelopment of a solvent selection guide for aldehyde-based direct reductive amination processes.鈥澨Green Chemistry听15 (2013): 1159-1165. Web. DOI: 10.1039/c3gc40359a
Prat, Denis, et. al. "CHEM21 selection guide of classical- and less classical-solvents."听Green Chemistry听18听(2016)听288-296. Web.听DOI: 10.1039/c5gc01008j
Prat, Denis, et. al. 鈥淪anofi鈥檚 Solvent Selection Guide: A Step Toward More Sustainable Processes.鈥澨Organic Process Research & Development听17 (2013): 1517-1525. Web. DOI: 10.1021/op4002565